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Anti-BCL10 Antibody EP606Y
Also for BCL10 (NM_003921)
|A synthetic peptide corresponding to residues in the C-term of human Bcl-10 was used as immunogen.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
|WB, IHC, IF
||WB: 1:1,000-5,000; IHC: 1:100-250; ICC: 1:100-250; IP: 1:50
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Does not react with Mouse, Rat
|Homo sapiens B-cell CLL/lymphoma 10 (BCL10)|
|c-E10; CARMEN; CIPER; CLAP; IMD37; mE10|
Entrez Gene 8915 Human
|This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [provided by RefSeq]. |
|Druggable Genome T cell receptor signaling pathwayB cell receptor signaling pathway|
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Western blot - Bcl10 antibody [EP606Y]; Anti-Bcl10 antibody [EP606Y] at 1/5000 dilution + Raji cell lysate.Predicted band size : 31 kDa.Observed band size : 32 kDa .
Western blot ; Anti-Bcl10 antibody [EP606Y] at 1/1000 dilution + Human Bcl10 full length protein at 0.01 ug.Secondary.Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed at 1/5000 dilution.developed using the ECL technique.Performed under reducing conditions.Exposure time : 1 minute
Immunohistochemistry (Paraffin-embedded sections) - Bcl10 antibody [EP606Y]; TA303755, at a 1/100 dilution, staining human hepatocellular carcinoma by Immunohistochemistry, Paraffin embedded tissue.
Immunofluorescence - Bcl10 antibody [EP606Y]; TA303755, staining Hela cells by Immunofluorescent.