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Home Antibody All anti-BCAR3 antibodies

Anti-BCAR3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305647
  • Goat Anti-BCAR3 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401187) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for BCAR3 (NM_003567)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide with sequence C-RKLEPPPVKQAEL, from the C Terminus of the protein sequence according to NP_003558.1.
Clone Name IsotypeGoat IgG
Species ReactivityHuman, Dog, porcine, Cow Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-2ug/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens breast cancer anti-estrogen resistance 3 (BCAR3), transcript variant 2
Alternative NameNSP2; SH2D3B
Database LinkNP_003558
FunctionBreast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. [provided by RefSeq].
Related Pathway

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WB Image
TA305647 (0.5ug/ml) staining of Mouse Kidney epithelial cells lysate (15ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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