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Anti-BBS4 TRUEMAB Antibody Clone OTI2D5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA804560 BBS4 mouse monoclonal antibody, clone OTI2D5 (formerly 2D5) 100ul 325
In Stock
LC409788 BBS4 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF804560 Carrier-free (BSA/glycerol-free) BBS4 mouse monoclonal antibody, clone OTI2D5 (formerly 2D5) 100ug $450 3-4 Weeks
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OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 266-519 of human BBS4 (NP_149017) produced in E.coli.
Clone NameClone OTI2D5 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
Predicted MW Explanation 58.1 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens Bardet-Biedl syndrome 4 (BBS4), transcript variant 1
Alternative NameBardet-Biedl syndrome 4
Database LinkNP_149017
Entrez Gene 585 Human
FunctionThis gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein 'BBSome' complex with six other BBS proteins. Alternative splice variants have been described but their predicted protein products have not been experimentally verified.[provided by RefSeq, Jan 2009].
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BBS4 (RC206210, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BBS4.


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