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Home Antibody All anti-BBC3 antibodies

Anti-BBC3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA321834
  • Anti-BBC3 Rabbit Polyclonal Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402330) , 20ug Explanation
100ul 325 2-3 Weeks
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Also for BBC3 (NM_014417)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to a region derived from 180-193 amino acids of Human Bcl-2-binding component 3
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1.1mg/ml
Guaranteed Application * Suggested DilutionsELISA: 1:1000-5000, WB: 1:500-2000
Predicted MW Explanation 21kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens BCL2 binding component 3 (BBC3), transcript variant 4
Alternative NameJFY-1; JFY1; PUMA
Database LinkNP_055232
Entrez Gene 27113 Human
Entrez Gene 170770 Mouse
Entrez Gene 317673 Rat
FunctionThis gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role; this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.
Related PathwayDruggable Genome p53 signaling pathwayHuntington's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

 

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