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Home Antibody All anti-BANF1 antibodies

Anti-BANF1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306383 Rabbit Polyclonal BANF1 Antibody 100ug $325 3-7 Days
LC428445 BANF1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IF(1)

OriGene Data

ImmunogenBANF1 antibody was raised against a 19 amino acid peptide from near the amino terminus of human BANF1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 0.5 - 2 ug/ml, IF
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens barrier to autointegration factor 1 (BANF1), transcript variant 2
Alternative NameBAF; BCRP1; D14S1460; NGPS
Database LinkNP_001137457
Entrez Gene 8815 Human
Entrez Gene 23825 Mouse
Entrez Gene 114087 Rat
FunctionBarrier-to-autointegration factor 1 (BANF1) is a conserved chromatin protein that non-specifically binds double-stranded DNA. BAF also interacts with a family of nuclear proteins that include LAP2, emerin, and MAN1. It is also a host cell component of retroviral pre-integration complexes (PICs), including that of HIV. BAF will bind to p55 Gag (the structural precursor of HIV-1 virions) as well as its cleaved product matrix. In addition to being a host cell component of the PIC, it is thought that BAF is also present at low levels in incoming virions, and thus might contribute to the assembly or activity of HIV-1 PICs through direct binding to matrix as well as DNA. Despite its predicted molecular weight, BANF1 often migrates at a higher size in SDS-PAGE.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of BANF1 in mouse kidney tissue lysate with BANF1 antibody at (A) 0.5, (B) 1 and (C) 2 ug/mL.
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Immunofluorescence of BANF1 in human kidney tissue with BANF1 antibody at 20 ug/mL.
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