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Home Antibody All anti-BAK1 antibodies

Anti-BAK1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA321299
  • Anti-BAK1 rabbit polyclonal antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400476) , 20ug
100ul 325 2-3 Weeks
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WB(1)
IHC(1)

OriGene Data

ImmunogenFusion protein corresponding to a region derived from 4-187 amino acids of human BCL2-antagonist/killer 1
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1.8mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:2000-5000, WB: 1:1000-5000,IHC: 1:50-200
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens BCL2-antagonist/killer 1 (BAK1)
Alternative NameBAK; BAK-LIKE; BCL2L7; CDN1
Database LinkNP_001179
FunctionThe protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.?
Related Pathway
Apoptosis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 23kDa. Positive control: Hela, A431, 293T and Jurkat cell lysate. Recommended dilution: 1/1000-5000. (Gel: 12%SDS-PAGE Lane1-4: Hela, A431, 293T and Jurkat cell lysate Lysates: 40 ug per lane Primary antibody: 1/900 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 5 seconds)
IHC Image
Predicted cell location: Cytoplasm. Positive control: Human esophagus cancer tissue. Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin-embedded human esophagus cancer tissue using BAK1 antibody at dilution 1/50, on the right is treated with the fusion protein. (Original magnification:x200)

 

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