Home Antibody All anti-BAK1 antibodies
Also for BAK1 (NM_001188)
| Peptide with sequence ASGQGPGPPRQE-C, from the N Terminus of the protein sequence according to NP_001179.|
|Test: Human. Expected from seq similarity: Human, Mouse, Rat, Pig
||Lot dependent; please refer to CoA along with shipment
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
|Homo sapiens BCL2-antagonist/killer 1 (BAK1)|
|BAK; BAK-LIKE; BCL2L7; CDN1|
Entrez Gene 578 Human
Entrez Gene 12018 Mouse
Entrez Gene 116502 Rat
|The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq]. |
|TransmembraneStem cell - PluripotencyDruggable Genome |
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TA302647 staining (0.5µg/ml) of A431 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.