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Home Antibody All anti-BAIAP2 antibodies

Anti-BAIAP2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA323917
  • Anti-BAIAP2 Rabbit Polyclonal Antibody
100ul 325 2-3 Weeks
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IHC(1)
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Also for BAIAP2 (NM_017451)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

Immunogen Fusion protein corresponding to a region derived from 1-179 amino acids of human
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:2000-5000, IHC: 1:50-200
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens BAI1-associated protein 2 (BAIAP2), transcript variant 2
Alternative NameBAP2; FLAF3; IRSP53
Database LinkNP_059345
Entrez Gene 10458 Human
Entrez Gene 108100 Mouse
Entrez Gene 117542 Rat
FunctionThe protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins; which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene; which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms
Related PathwayDruggable Genome Adherens junctionRegulation of actin cytoskeleton

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

IHC Image
Predicted cell location: Cytoplasm, Cell membrane. Positive control: Human colon cancer tissue. Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using BAIAP2 antibody at dilution 1/50, on the right is treated with the fusion protein. (Original magnification: x200)

 

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