OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-BAG4 antibodies

Anti-BAG4 Antibody EPR3597

div

Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307269
  • Rabbit monoclonal antibody against SODD(clone EPR3597)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417692) , 20ug Explanation
100ul $325 3-7 Days
Add to Shopping Cart
spacer
WB(1)
IHC(2)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human SODD was used as an immunogen.
Clone NameEPR3597 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250
BufferpH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens BCL2-associated athanogene 4 (BAG4), transcript variant 1
Alternative NameBAG-4; SODD
Database LinkNP_004865
Entrez Gene 9530 Human
FunctionSODD (BAG4) is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. SODD was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost (1).
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-Silencer of Death Domain antibody [EPR3597]; All lanes : Anti-Silencer of Death Domain antibody [EPR3597] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : MOLT4 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 50 kDa.
spacer
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Silencer of Death Domain antibody [EPR3597]; Immunohistochemical analysis of paraffin-embedded Human colon adenocarcinoma tissue labelling Silencer of Death Domain with TA307269 at 1/100 dilution.
spacer
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Silencer of Death Domain antibody [EPR3597]; Immunohistochemical analysis of paraffin-embedded Human kidney tissue labelling Silencer of Death Domain with TA307269 at 1/100 dilution.
spacer

 

spacer
Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title