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Home Antibody All anti-BAG2 antibodies

Anti-BAG2 Antibody EPR3568

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307311
  • Rabbit monoclonal antibody against Bag-2 (clone EPR3568 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418098) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IF(1)
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Also for BAG2 (NM_004282)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the C-terminus of human Bag-2 was used as immunogen.
Clone NameEPR3568 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:1000 - 1:2000; ICC/IF: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens BCL2-associated athanogene 2 (BAG2)
Alternative NameBAG-2; dJ417I1.2
Database LinkNP_004273
Entrez Gene 9532 Human
Entrez Gene 213539 Mouse
Entrez Gene 690038 Rat
FunctionBAG-2 is a member of a family of BAG-related proteins (BAG-2, BAG-3, BAG-4, BAG-5). BAG-family proteins may play a role in providing opportunities for specification and diversification of Heat Shock Protein (Hsp70) chaperone functions. Hsp70 family molecular chaperones play critical roles in protein folding and trafficking in all eukaryotic cells. BAG-1 binds the ATPase domains of Hsp70 and Hsc70, modulating their chaperone activity and functioning as a competitive antagonist of the co-chaperone Hip. BAG-2 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner (1).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - BAG2 antibody [EPR3568]; All lanes : Anti-BAG2 antibody [EPR3568] at 1/2000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : A549 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 24 kDa.Observed band size : 24 kDa.
IF Image
Immunocytochemistry/ Immunofluorescence - BAG2 antibody [EPR3568]; Immunofluorescence analysis of HeLa cells with 1/100 TA307311.

 

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