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Home Antibody All anti-BAG2 antibodies

Anti-BAG2 Antibody EPR3567

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307310
  • Rabbit monoclonal antibody against Bag-2 (clone EPR3567 )
  • FREE positive control: HEK293T cell transient overexpression lysate (LC418098) , 20ug
100ul $325 In Stock
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WB(1)
IHC(1)
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Also for BAG2 (NM_004282)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the N-terminus of human Bag-2 was used as immunogen.
Clone NameEPR3567 IsotypeIgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsFC: 1:60, ICC: 1:100 - 250, IHC: 1:100, IP: 1:10, WB: 1:1000 - 5000,
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens BCL2-associated athanogene 2 (BAG2)
Alternative NameBAG-2; dJ417I1.2
Database LinkNP_004273
FunctionBAG-2 is a member of a family of BAG-related proteins (BAG-2, BAG-3, BAG-4, BAG-5). BAG-family proteins may play a role in providing opportunities for specification and diversification of Heat Shock Protein (Hsp70) chaperone functions. Hsp70 family molecular chaperones play critical roles in protein folding and trafficking in all eukaryotic cells. BAG-1 binds the ATPase domains of Hsp70 and Hsc70, modulating their chaperone activity and functioning as a competitive antagonist of the co-chaperone Hip. BAG-2 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner (1).
Related Pathway

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WB Image
Western blot - BAG2 antibody [EPR3567]; All lanes : Anti-BAG2 antibody [EPR3567] at 1/5000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : HepG2 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 24 kDa.Observed band size : 24 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - BAG2 antibody [EPR3567]; TA307310, at 1/100 dilution, staining BAG2 in human ovarian carcinoma by Immunohistochemistry using paraffin-embedded tissue.

 

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