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Home Antibody All anti-B2M antibodies

Anti-B2M Antibody Polyclonal

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA319617 Rabbit Polyclonal B2M Antibody 100ug $325 3-7 Days
LC401311 B2M HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)

OriGene Data

ImmunogenB2M antibody was raised against a 15 amino acid peptide near the carboxy terminus of human B2M.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsELISA, WB: 1 - 2 ug/ml
Predicted MW Explanation Predicted: 13 kDa Observed: 12 kDa
BufferB2M Antibody is supplied in PBS containing 0.02% sodium azide.
Purification B2M Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens beta-2-microglobulin (B2M)
Alternative Namebeta chain of MHC class I molecules; beta-2-microglobin; beta-2-microglobulin
Database LinkNP_004039
Entrez Gene 567 Human
FunctionB2M Antibody: Beta2-microglobulin (B2M) is a principal component of the Major Histocompatibility Complex (MHC) class I molecule, a ternary membrane protein complex that displays fragments derived from proteolyzed cytosolic proteins on the surface of cells for recognition by the surveillance immune system (1,2). B2M is involved in the presentation of peptide antigens to the immune system and plays a critically important role in immune system function (3). It is expressed on nearly all nucleated cells and contains one Ig-like C1-type (immunoglobulin-like) domain (2,3). Mutations in the Beta 2-microglobulin gene can enhance the progression of malignant melanoma and osteoarthropathy (4,5).
Related PathwaySecreted ProteinDruggable Genome Antigen processing and presentation

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of B2M in SK-N-SH cell lysate with B2M antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
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