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Home Antibody All anti-Angptl4 antibodies

Anti-Angptl4 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA318914
  • Rabbit polyclonal anti-Angptl4 (FIAF) antibody
100ug 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenSynthetic peptide surrounding amino acid 84 of mouse FIAF
Clone Name IsotypeRabbit IgG
Species ReactivityMouse, rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4ug/ml
Buffer100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens angiopoietin-like 4 (ANGPTL4), transcript variant 2
Alternative NameARP4, FIAF, PGAR, HFARP, PPARG, pp1158, ANGPTL2
Database LinkNP_057193
FunctionAdipose tissue is an energy reserve in animals. Adipose cells produce and secrete numerous physiologically important proteins that help regulate whole body metabolism, such as adiponectin leptin. Fasting causes significant changes in nutrient metabolism and many of these changes are controlled by transcription factors that regulate rate-limiting enzymes. An important transcription factor that mediates metabolic processes induced by fasting is peroxisome proliferator-activated receptor alpha (PPAR alpha). PPAR alpha has recently been reported to target a novel gene encoding the secreted protein FIAF (fasting-induced adipose factor). FIAF is expressed predominantly in adipose tissue and is strongly upregulated in white adipose tissue and the liver under fasting conditions. Initial studies suggest that FIAF represents a novel endocrine signal helping to regulate metabolism, especially under fasting conditions.
Related Pathway

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WB Image
Western blot analysis of FIAF expression in rat adipose tissue extract.

 

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