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Home Antibody All anti-AXIN1 antibodies

Anti-AXIN1 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319744 Rabbit Polyclonal AXIN1 Antibody 100ug $325 3-7 Days
LC418638 AXIN1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenAXIN1 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human AXIN1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 - 2 ug/mL, IF: 20 ug/mL
BufferAXIN1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification AXIN1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens axin 1 (AXIN1), transcript variant 1
Alternative NameAXIN; PPP1R49
Database LinkNP_003493
Entrez Gene 8312 Human
Entrez Gene 12005 Mouse
Entrez Gene 79257 Rat
FunctionAXIN1 Antibody: AXIN1 is a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain and is thought to function as a negative regulator of the WNT signaling pathway that regulates embryonic axis formation. AXIN1 interacts with adenomatosis polyposis coli (APC), beta-catenin, glycogen synthase kinase 3 beta, forming a tetrameric complex resulting in the regulation of the stabilization of beta-catenin. Mutations in the AXIN1 gene have been associated various carcinomas, indicating that it also functions as a tumor suppressor.
Related PathwayStem cell relevant signaling - Wnt Signaling pathwayES Cell Differentiation/IPSDruggable Genome Wnt signaling pathwayPathways in cancerColorectal cancerEndometrial cancerBasal cell carcinoma

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of AXIN1 in SK-N-SH cell lysate with AXIN1 antibody at 1 ug/mL.

IF Image
Immunofluorescence of AXIN1 in human brain tissue with AXIN1 antibody at 20 ug/mL.


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