Anti-ATP2A1 Antibody, EPR7321

Also for ATP2A1 (NM_004320)

OriGene Data

Immunogen	A synthetic peptide corresponding to residues near the N-terminus of human ATP2A1 was used as an immunogen.
Clone Name	EPR7321	Isotype
Species Reactivity	Human	Concentration
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB: 1:1,000 - 10,000; IP: 1:10 - 100; FC: 1:10 - 100;
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (ATP2A1), transcript variant a
Alternative Name	ATP2A; SERCA1
Database Link	NP_004311
Function	ATP2A1 is one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and it is involved in muscular excitation and contraction. Mutations in ATP2A1 cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise (1).
Related Pathway

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WB Image

Western blot analysis on fetal muscle lysate using anti-ATP2A1 RabMAb.

IHC Image

Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue using anti-ATP2A1 RabMAb.

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
Biotin
PE
FITC
DyLight® 488
DyLight® 550
DyLight® 594
DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Anti-ATP2A1 Antibody EPR7321

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data