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Anti-ATIC TRUEMAB Antibody Clone 4A10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA504570
  • ATIC mouse monoclonal antibody,clone 4A10
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418255) , 20ug Explanation
100ul 325 In Stock
CF504570
  • Carrier-free (BSA/glycerol-free) ATIC mouse monoclonal antibody,clone 4A10
100ug $450 3-4 weeks
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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Also for ATIC (NM_004044)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human ATIC(NP_004035) produced in HEK293T cell.
Clone NameClone 4A10 IsotypeIgG1
Species ReactivityHuman , Dog Concentration3.51 mg/ml
Guaranteed Application *WB Suggested DilutionsWB 1:500~1000,
Predicted MW Explanation 64.4 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC)
Alternative NameAICAR; AICARFT; HEL-S-70p; IMPCHASE; PURH
Database LinkNP_004035
Entrez Gene 471 Human
Entrez Gene 488513 Dog
FunctionThis gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq].
Related PathwayStem cell - Pluripotency Purine metabolismOne carbon pool by folateMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATIC (RC203490, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ATIC.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by usin g anti-ATIC monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

 

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