Home Antibody All anti-ATG3 antibodies
Anti-ATG3 Antibody Polyclonal
Also for ATG3 (NM_022488)
|ATG3 antibody was raised against an 18 amino acid synthetic peptide near the center of human ATG3.|
|Human, Mouse, Rat
||WB: 1 - 2 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
|ATG3 Antibody is supplied in PBS containing 0.02% sodium azide.|
|ATG3 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens autophagy related 3 (ATG3), transcript variant 1|
|APG3; APG3-LIKE; APG3L; PC3-96|
Entrez Gene 64422 Human
Entrez Gene 67841 Mouse
Entrez Gene 171415 Rat
|ATG3 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG3 (APG3) is a widely expressed conjugating enzyme for APG8 lipidation, an essential step for the initiation of autophagy. It functions as an E2-like enzyme during the initial stages of autophagosome formation by catalyzing the formation of the Atg8-phosphatidylethanolamine (Atg8-PE) conjugate, which is critical for autophagy. |
| Regulation of autophagy|
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Western blot analysis of ATG3 in Mouse kidney tissue Lysate with ATG3 antibody at (A) 1 and (B) 2 ug/mL.
Immunofluorescence of ATG3 in human kidney with ATG3 antibody at 20 ug/mL.