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Anti-ATF2 Antibody E243
Also for ATF2 (NM_001880)
|A synthetic peptide corresponding to residues in C-terminus of human ATF2 was used as immunogen. The antibody does not cross-react with other ATF family members.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:10,000; IHC: 1:250-500; ICC: 1:250500; IP: 1:60
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Does not react with Mouse, Rat
|Homo sapiens activating transcription factor 2 (ATF2), transcript variant 1|
|CRE-BP1; CREB2; HB16; TREB7|
|This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. [provided by RefSeq]. |
MAPK signaling pathway
TGF Beta Signaling Pathway
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Western blot - ATF2 antibody [E243]; Anti-ATF2 antibody [E243] at 1/10000 dilution + HeLa cell lysate.Predicted band size : 54 kDa.Observed band size : 70 kDa .
Immunohistochemistry (Paraffin-embedded sections) - ATF2 antibody [E243]; Ab32160, at a dilution of 1/250, staining ATF2 in paraffin embedded breast carcinoma tissue by Immunohistochemistry.