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Home Antibody All anti-ARRB2 antibodies

Anti-ARRB2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303022
  • Goat Polyclonal Antibody against ARRB2
100ug 325 3-7 Days
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WB(1)

OriGene Data

Immunogen Peptide with sequence C-HDHIPLPRPQS, from the internal region of the protein sequence according to NP_004304.1; NP_945355.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human, Mouse, Rat. Expected from seq similarity: Human, Mouse, Rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:32,000. WB: 0.03-0.1µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens arrestin, beta 2 (ARRB2), transcript variant 1
Alternative NameARB2; ARR2; BARR2
Database LinkNP_004304
Entrez Gene 409 Human
Entrez Gene 216869 Mouse
Entrez Gene 25388 Rat
FunctionMembers of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq].
Related PathwayDruggable Genome MAPK signaling pathwayChemokine signaling pathwayEndocytosisOlfactory transduction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA303022 (0.03µg/ml) staining of Human Spleen lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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