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Home Antibody All anti-APP antibodies

Anti-APP Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308848
  • Rabbit Polyclonal antibody to beta Amyloid (amyloid beta (A4) precursor protein)
100ul 325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 602 and 757 of Human APP
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration0.2mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB:1:500-1:3000;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens amyloid beta (A4) precursor protein (APP), transcript variant 7
Alternative NameAAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2
Database LinkNP_001129603
FunctionThis gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq]
Related Pathway
Delta-Notch Signaling Pathway
Hemostasis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample(30 ug of whole cell lysate) A:HepG2 (anti-APP antibody diluted at 1:1500
IHC Image
Immunohistochemical analysis of paraffin-embedded Tonsil, plasma cells, using beta A4 Amyloid(anti-APP antibody) antibody(10 ?g/ml).

 

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