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Home Antibody All anti-APOA5 antibodies

Anti-APOA5 Antibody 1G5G9

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301561
  • Mouse Monoclonal Antibody against Apo A5 (1G5G9)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC403279) , 20ug
100ul $325 3-7 Days
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WB(2)
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Also for APOA5 (NM_052968)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenNi-NTA purified full-length recombinant human APOA5 expressed in E. Coli strain BL21 (DE3).
Clone Name1G5G9 IsotypeIgG1 kappa
Species Reactivityhuman Concentration3.6 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1:2000
Buffer

Reference Data

Target NameHomo sapiens apolipoprotein A-V (APOA5), transcript variant 1
Alternative NameAPOAV; RAP3
Database LinkNP_443200
FunctionApolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four-fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor-4 (PPAR-alpha) agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentrations than other apolipoproteins.
Related Pathway

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WB Image
Western blot analysis using anti- human APOA5 monoclonal antibody against human serum total protein (lane 2). Lane 1 is a MW standard
WB Image
Western Blot: Apolipoprotein A5 Antibody (1G5G9) - Detection of Apo A5 in HepG2 cell lysate.

 

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