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OriGene Antibodies in recent publications

A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]

Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]

Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]

Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]

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Home All anti-APEX1 antibodies

Anti-APEX1 TrueMAB Antibody clone 2A4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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SKU	Description	Amount	Price	Availability*
TA800333	Purified APEX1 mouse monoclonal antibody,clone 2A4 FREE positive control: HEK293T cell transient overexpression lysate (LC400618) , 20ug	100ul	$325	In Stock
CF800333	Carrier-free (BSA/glycerol-free) APEX1 mouse monoclonal antibody,clone 2A4	100ug	$450	8-10 Days

WB(1)

IHC(20)

IF(1)

FC(1)

Also for APEX1 (NM_001641)

Gene Name	Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 (APEX1), transcript variant 1
Synonyms:	APE; APE1; APEN; APEX; APX; HAP1; REF1
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-242 of human APEX1 (NP_001632) produced in E.coli.
Buffer	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone Name	clone 2A4	Isotype	IgG2a
Species Reactivity	Human	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *	WB, IHC, IF, FC	Suggested Dilutions	WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100,
Background	Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq].
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY APEX1 (RC201732, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-APEX1.

Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-APEX1 mouse monoclonal antibody. (TA800333)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-APEX1 mouse monoclonal antibody. (TA800333)

Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-APEX1 mouse monoclonal antibody. (TA800333)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-APEX1 mouse monoclonal antibody. (TA800333)

Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-APEX1 mouse monoclonal antibody. (TA800333)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-APEX1 mouse monoclonal antibody. (TA800333)

Immunohistochemical staining of paraffin-embedded Human lung tissue using anti-APEX1 mouse monoclonal antibody. (TA800333)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-APEX1 mouse monoclonal antibody. (TA800333)

Immunohistochemical staining of paraffin-embedded Human Ovary tissue using anti-APEX1 mouse monoclonal antibody. (TA800333)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-APEX1 mouse monoclonal antibody. (TA800333)

Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-APEX1 mouse monoclonal antibody. (TA800333)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-APEX1 mouse monoclonal antibody. (TA800333)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-APEX1 mouse monoclonal antibody. (TA800333)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-APEX1 mouse monoclonal antibody. (TA800333)

Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-APEX1 mouse monoclonal antibody. (TA800333)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-APEX1 mouse monoclonal antibody. (TA800333)

Immunohistochemical staining of paraffin-embedded Human bladder tissue using anti-APEX1 mouse monoclonal antibody. (TA800333)

Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-APEX1 mouse monoclonal antibody. (TA800333)

Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-APEX1 mouse monoclonal antibody. (TA800333)

Immunohistochemical staining of paraffin-embedded Human tonsil using anti-APEX1 mouse monoclonal antibody. (TA800333)

Anti-APEX1 mouse monoclonal antibody (TA800333) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY APEX1(RC201732).

HEK293T cells transfected with either RC201732 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-APEX1 antibody(TA800333), and then analyzed by flow cytometry.

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