OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-APEX1 antibodies

Anti-APEX1 Antibody

div

Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308774 Rabbit polyclonal antibody to APE1 (APEX nuclease (multifunctional DNA repair enzyme) 1) 100ul $325 3-7 Days
LC429949 APEX1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
Add to Shopping Cart
spacer
WB(1)
IHC(1)
IF(1)
spacer
Also for APEX1 (NM_080649)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 1 and 45 of APE1 (Uniprot ID#P27695)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Pig, Rhesus Monkey, Chimpanzee) Concentration5.04mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 36kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Affinity purified by Protein A.
Note Seq homology of immunogen across species: Pig (93%), Rhesus Monkey (100%), Chimpanzee (100%)

Reference Data

Target NameHomo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 (APEX1), transcript variant 3
Alternative NameAPE; APE1; APEN; APEX; APX; HAP1; REF1
Database LinkNP_542380
Entrez Gene 328 Human
Entrez Gene 702757 Monkey
FunctionApurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq]
Related PathwayStem cell - PluripotencyTranscription FactorsDruggable Genome Base excision repair

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: A549. 10% SDS PAGE. TA308774 diluted at 1:3000.
spacer
APE1 antibody [N1], N-term detects APEX1 protein at nucleus on Saos2 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded Saos2 xenograft. APE1 antibody [N1], N-term (TA308774) dilution: 1:500.
spacer
Immunofluorescence analysis of paraformaldehyde-fixed A431, using APE1(TA308774) antibody at 1:200 dilution.
spacer

 

spacer
Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title

Notice to Non-US Customers

ExclaimationWeb price and delivery time are for direct sales only.

Non-US customers are encouraged to contact our dedicated distributor network for quotes and streamlined ordering/delivery support.

Acknowledge