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Anti-APEX1 Antibody

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

WB(1)

IF(1)

OriGene Data

Immunogen	Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 15 of APE1
Clone Name		Isotype	IgG
Species Reactivity	Human	Concentration	5.04mg/ml
Guaranteed Application *	WB, IF	Suggested Dilutions	WB:1:500-1:3000; IF:1:100-1:200;
Buffer	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification	Affinity purified by Protein A. (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 (APEX1), transcript variant 3
Alternative Name	APE; APE1; APEN; APEX; APX; HAP1; REF1
Database Link	NP_542380
Function	Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq]
Related Pathway

Related Lysate from OriGene • Transient overexpression lysate of APEX nuclease (multifunctional DNA repair enzyme) 1 (APEX1), transcript variant 3 • Transient overexpression lysate of APEX nuclease (multifunctional DNA repair enzyme) 1 (APEX1), transcript variant 3 Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • APEX1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • APEX1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Apex1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • APEX1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Apex1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 (APEX1), transcript variant 3 as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 (APEX1), transcript variant 3 as transfection-ready DNA • Lenti ORF clone of Human APEX nuclease (multifunctional DNA repair enzyme) 1 (APEX1), transcript variant 3 , Myc-DDK-tagged • Lenti ORF clone of Human APEX nuclease (multifunctional DNA repair enzyme) 1 (APEX1), transcript variant 3, mGFP tagged Related cDNA Clones • Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 (APEX1), transcript variant 3 as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)