OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-APCS antibodies

Anti-APCS Antibody EP1018Y

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300707
  • Rabbit Monoclonal Antibody against APCS (Clone EP1018Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400617) , 20ug
100ul 325 In Stock
Add to Shopping Cart
WB(1)
IHC(1)
spacer
Also for APCS (NM_001639)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-term of human SAP was used as an immunogen.
Clone NameEP1018Y IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1e+006; IHC-P: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens amyloid P component, serum (APCS)
Alternative NameHEL-S-92n; PTX2; SAP
Database LinkNP_001630
FunctionSerum Amyloid P (SAP) is a non-fibrillar plasma glycoprotein that belongs to the pentraxin family. It is universally found in amyloid deposits and this is probably due to its specific calcium-dependent binding to motifs present on all types of amyloid fibrils. SAP is also found to prevent fibrillar breakdown by enzymes and it is believed that it helps maintains stability of the amyloid deposits (1,2). It has been shown that SAP binds monocytes with high avidity, but does not bind to erythrocytes, NK cells, T lymphocytes or B lymphocytes (3). SAP production can be induced by exposure to IL-1, IL-6 and IFN-beta. The SAP-inducing activity was neutralized by antibodies to each of the recombinant cytokines (4).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Amyloid P component antibody [EP1018Y]; Anti-Serum Amyloid P antibody [EP1018Y] at 1/1000000 dilution + Human serum membrane at 10 ug.Secondary.Goat anti-rabbit HRP labelled, at 1/2000 dilution.Predicted band size : 25 kDa.Observed band size : 25 kDa.
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - Amyloid P component antibody [EP1018Y]; Ab45151 (1:100) staining human Amyloid P component in human kidney by immunohistochemistry using paraffin embedded tissue.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title