OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-APC antibodies

Anti-APC Antibody EP701Y

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303394
  • Rabbit monoclonal antibody against APC (EP701Y)
100ul 325 In Stock
Add to Shopping Cart
WB(1)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus of human APC was used as immunogen. This antibody is predicted to detect isoform 2 based on sequence analysis.
Clone NameEP701Y IsotypeIgG
Species ReactivityRat, Human (Does not react with: Mouse) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500-1,000; IHC: 1:50-100; ICC: 50-100; IP: 1:50
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse

Reference Data

Target NameHomo sapiens adenomatous polyposis coli (APC), transcript variant 3
Alternative NameBTPS2; DP2; DP2.5; DP3; GS; PPP1R46
Database LinkNP_000029
FunctionThis gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq].
Related Pathway
Wnt Signaling Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - APC antibody [EP701Y]; Anti-APC antibody [EP701Y] at 1/1000 dilution + 10 ug/ml HEK293 cell lysate.Secondary.1:2000 goat anti-rabbit HRP labeled .Observed band size : 160 kDa .Additional bands at : 250 kDa. We are unsure as to the identity of these extra bands.
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - APC antibody [EP701Y]; TA303394 (1:50), staining human colon carcinoma by immunohistochemistry, paraffin-embedded tissue.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title