Home Antibody All anti-APBB1 antibodies
Also for APBB1 (NM_001164)
|Recombinant rat protein expressed in bacteria.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
||WB: 1: 1000
|PBS, 15% glycerol and 0.02% sodium azide|
|Homo sapiens amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) (APBB1), transcript variant 1|
|FE65; MGC:9072; RIR|
|FE65 is a signaling adaptor of APP protein. The FE65/APP complex was shown to translocate into the cell nucleus and regulate gene expression. Genetic studies in mice validated FE65-APP interaction and molecular studies provided evidence on the role of the complex in abnormal signaling detected in brains of Alzheimer Disease patients.|
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Detection of FE65 protein in HEK 293 cell lysate
Western Blot: FE65 Antibody - Cells were transfected with the pCMV6-ENTRY control or pCMV6-ENTRY APBB1 cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-APBB1.