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Anti-APBA1 Antibody Polyclonal
Also for APBA1 (NM_001163)
|APBA1 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human APBA1.|
|Human, Mouse, Rat
||WB: 0.5 ug/ml, IF: 20 ug/ml
|APBA1 Antibody is supplied in PBS containing 0.02% sodium azide.|
|APBA1 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens amyloid beta (A4) precursor protein-binding, family A, member 1 (APBA1)|
|D9S411E; LIN10; MINT1; X11; X11A; X11ALPHA|
|APBA1 Antibody: The Amyloid beta 4 (A4) precursor protein-binding family A member 1 (APBA1) is a member of the X11 protein family and a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). APBA1 stabilizes APP and inhibits production of proteolytic APP fragments including the Aβ peptide that is deposited in the brains of Alzheimer's disease patients. It is thought to be involved in signal transduction processes and is a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. APBA1 can also bind to CASK, a multidomain scaffolding protein involved in brain development and synapse formation. |
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Western blot analysis of APBA1 in rat brain tissue lysate with APBA1 antibody at 0.5 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Immunofluorescence of APBA1 in human brain tissue with APBA1 antibody at 20 ug/mL.