EGFR Rabbit Polyclonal Antibody

CAT#: AP02093SU-N

EGFR rabbit polyclonal antibody, Serum

Size: 20 ul 100 ul


USD 310.00

2 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Applications ELISA, IF, WB
Recommended Dilution ELISA: 1/10.000 (Ref.1).
Immunfluorescence: 1/1000.
Western blot: 1/500.
Reactivities Human
Host Rabbit
Clonality Polyclonal
Immunogen Human native EGF-Receptor
Specificity This antibody detects EGF-Receptor.
Formulation State: Serum
State: Lyophilized serum
Reconstitution Method Restore in aqua bidest to initial volume.
Conjugation Unconjugated
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes, classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
Synonyms Epidermal growth factor receptor, EGF Receptor, erbB-1, c-ErbB-1
Note LocusID 1956
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.