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Home Antibody All anti-ANP32A antibodies

Anti-ANP32A Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306129
  • Rabbit Polyclonal PHAP Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416747) , 20ug Explanation
100ug $325 3-7 Days
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WB(1)
IF(1)
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Also for ANP32A (NM_006305)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenPHAP antibody was raised with a synthetic peptide corresponding to amino acids at amino terminus of human PHAP.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 ug/ml, IHC: 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens acidic (leucine-rich) nuclear phosphoprotein 32 family, member A (ANP32A)
Alternative NameC15orf1; HPPCn; I1PP2A; LANP; MAPM; PHAP1; PHAPI; PP32
Database LinkNP_006296
Entrez Gene 8125 Human
Entrez Gene 11737 Mouse
Entrez Gene 25379 Rat
FunctionApoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis (1). PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.
Related PathwayStem cell - PluripotencyDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of PHAP expression in human Raji cell lysate with PHAP antibody at 1 ug/mL. The wide and strong band below PHAP III is a doublelet composed of PHAP I (upper) and PHAP I2a (lower).
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Immunocytochemistry of PHAP in Raji cells with PHAP antibody at 1 ug/mL.
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