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Anti-ANKH Antibody EPR8092
Also for ANKH (NM_054027)
|A synthetic peptide corresponding to residues in extracellular domain of human ANKH was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; FC: 1:10 - 1:100
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for ICC/IF,IHC-P or IP.
|Homo sapiens ANKH inorganic pyrophosphate transport regulator (ANKH)|
|ANK; CCAL2; CMDJ; CPPDD; HANK; MANK|
|ANKH is a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in ANKH have been associated with autosomal dominant craniometaphyseal dysplasia (1). |
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Western blot - Anti-ANKH antibody [EPR8092]; All lanes : Anti-ANKH antibody [EPR8092] at 1/1000 dilution.Lane 1 : Fetal brain cell lysate.Lane 2 : 293T cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 54 kDa.Observed band size : 54 kDa.
Flow Cytometry - Anti-ANKH antibody [EPR8092]; Flow cytometric analysis of 293T cells using ab129001 at a 1/10 dilution (red), or a rabbit IgG (negative) (green).