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Anti-ANG Antibody Polyclonal
Also for ANG (NM_001097577)
|ANG antibody was raised against a 15 amino acid synthetic peptide near the center of human ANG.|
|Human, Mouse, Rat
||WB: 1 - 2 ug/ml, IF: 20 ug/ml
|ANG Antibody is supplied in PBS containing 0.02% sodium azide.|
|ANG Antibody is affinity chromatography purified via peptide column.
|Homo sapiens angiogenin, ribonuclease, RNase A family, 5 (ANG), transcript variant 2|
|ALS9; HEL168; RAA1; RNASE4; RNASE5|
Entrez Gene 283 Human
Entrez Gene 11727 Mouse
Entrez Gene 305843 Rat
|ANG Antibody: Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin is a genetic link between ALS and PD. |
|Secreted ProteinTransmembraneDruggable Genome |
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Western blot analysis of ANG in rat liver tissue lysate with Ang antibody at (A) 1 and (B) 2 ug/mL.
Immunofluorescence of ANG in human liver tissue with ANG antibody at 20 ug/mL.