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Home Antibody All anti-ANAPC7 antibodies

Anti-ANAPC7 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319926 Rabbit Polyclonal APC7 Antibody 100ug $325 3-7 Days
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Also for ANAPC7 (NM_016238)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenAPC7 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human APC7.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 - 2 ug/mL, IF: 20 ug/mL
BufferAPC7 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification APC7 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens anaphase promoting complex subunit 7 (ANAPC7), transcript variant 1
Alternative NameAPC7
Database LinkNP_057322
Entrez Gene 51434 Human
Entrez Gene 56317 Mouse
Entrez Gene 304490 Rat
FunctionAPC7 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC7 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC7 is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with various transcription coactivators.
Related PathwayDruggable Genome Cell cycleOocyte meiosisUbiquitin mediated proteolysisProgesterone-mediated oocyte maturation

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of APC7 in rat kidney tissue lysate with APC7 antibody at (A) 1 and (B) 2 ug/mL.

IF Image
Immunofluorescence of APC7 in rat kidney tissue with APC7 antibody at 20 ug/mL.


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