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Home Antibody All anti-ANAPC5 antibodies

Anti-ANAPC5 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319925
  • Rabbit Polyclonal APC5 Antibody
100ug 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for ANAPC5 (NM_016237)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenAPC5 antibody was raised against a 17 amino acid synthetic peptide near the center of human APC5.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
BufferAPC5 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification APC5 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens anaphase promoting complex subunit 5 (ANAPC5), transcript variant 1
Alternative NameAPC5
Database LinkNP_057321
FunctionAPC5 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC5 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. While little is known of APC5, it is thought that APC5 associates with other APC/C components APC1, APC4, and CDC23 interdependently, such that loss of any one subunit reduces binding between the remaining three.
Related Pathway
Cell cycle
TGF Beta Signaling Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of APC5 in human kidney tissue lysate with APC5 antibody at (A) 1 and (B) 2 ug/mL.
IHC Image
Immunohistochemistry of APC5 in rat kidney tissue with APC5 antibody at 5 ug/mL.
IF Image
Immunofluorescence of APC5 in rat kidney tissue with APC5 antibody at 20 ug/mL.

 

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