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Home Antibody All anti-ANAPC11 antibodies

Anti-ANAPC11 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319928 Rabbit Polyclonal APC11 Antibody 100ug $325 3-7 Days
LC424181 ANAPC11 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for ANAPC11 (NM_001002244)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenAPC11 antibody was raised against an 18 amino acid synthetic peptide near the center of human APC11.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 - 2 ug/mL, IF: 20 ug/mL
BufferAPC11 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification APC11 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens anaphase promoting complex subunit 11 (ANAPC11), transcript variant 1
Alternative NameAPC11; Apc11p; HSPC214
Database LinkNP_001002244
Entrez Gene 51529 Human
Entrez Gene 66156 Mouse
Entrez Gene 498030 Rat
FunctionAPC11 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC11 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC11, together with APC2 and Ubc4, form the minimal APC ubiquitin ligase module.
Related PathwayDruggable Genome Cell cycleOocyte meiosisUbiquitin mediated proteolysisProgesterone-mediated oocyte maturation

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of APC11 in 3T3 cell tissue lysate with APC11 antibody at (A) 1 and (B) 2 ug/mL.

IF Image
Immunofluorescence of APC11 in 3T3 cells with APC11 antibody at 20 ug/mL.


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