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Home Antibody All anti-ANAPC11 antibodies

Anti-ANAPC11 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319928
  • Rabbit Polyclonal APC11 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC424181) , 20ug
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for ANAPC11 (NM_001002244)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenAPC11 antibody was raised against an 18 amino acid synthetic peptide near the center of human APC11.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 - 2 ug/ml, IF: 20 ug/ml
BufferAPC11 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification APC11 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens anaphase promoting complex subunit 11 (ANAPC11), transcript variant 1
Alternative NameAPC11; Apc11p; HSPC214
Database LinkNP_001002244
FunctionAPC11 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC11 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC11, together with APC2 and Ubc4, form the minimal APC ubiquitin ligase module.
Related Pathway
Cell cycle

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WB Image
Western blot analysis of APC11 in 3T3 cell tissue lysate with APC11 antibody at (A) 1 and (B) 2 ug/mL.
IF Image
Immunofluorescence of APC11 in 3T3 cells with APC11 antibody at 20 ug/mL.

 

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