EGFR Mouse Monoclonal Antibody [Clone ID: 51CT78.40.5]

CAT#: AM11067SU-N

EGFR mouse monoclonal antibody, clone 51CT78.40.5, Ascites


USD 586.00

2 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Clone Name 51CT78.40.5
Applications WB
Recommended Dilution ELISA: 1/4000.
Western blotting: 1/2000.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Purified His-tagged EGFR protein( Fragment).
Specificity This antibody is specific to EGFR.
Formulation State: Ascites
State: Ascites containing 0.09% (W/V) Sodium Azide as preservative.
Conjugation Unconjugated
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name epidermal growth factor receptor
Background EGFR is a transmembrane glycoprotein that is a member of a family of protein tyrosine kinases crucial in maintaining a normal balance in cell growth and development. A prototype member of the type 1 receptor tyrosine kinases, EGFR is encoded by the cellular oncogene cerbB1. EGFR has an extracellular ligand binding domain, a single transmembrane region, and cytoplasmic domain which is composed of a tyrosine kinase domain and a carboxy terminal domain. The carboxy terminal domain contains at least four tyrosine autophosphorylation sites. Increased production or activation of EGFR has been associated with poor prognosis in a variety of tumors. EGFR overexpression is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
Synonyms Epidermal growth factor receptor, EGF Receptor, erbB-1, c-ErbB-1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.