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Home Antibody All anti-ALX4 antibodies

Anti-ALX4 TRUEMAB Antibody clone 2F2

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA505146
  • ALX4 mouse monoclonal antibody,clone 2F2
  • FREE positive control: HEK293T cell transient overexpression lysate (LC411892) , 20ug
100ul 325 In Stock
CF505146
  • Carrier-free (BSA/glycerol-free) ALX4 mouse monoclonal antibody,clone 2F2
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
FC(1)

OriGene Data

ImmunogenFull length human recombinant protein of human ALX4(NP_068745) produced in HEK293T cell.
Clone Nameclone 2F2 IsotypeIgG1
Species ReactivityHuman Concentration1.00 mg/ml
Guaranteed Application *WB, FC Suggested DilutionsWB 1:1000, FLOW 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens ALX homeobox 4 (ALX4)
Alternative NameCRS5; FND2
Database LinkNP_068745
FunctionThis gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart. [provided by RefSeq].
Related Pathway

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WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ALX4 (RC224459, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ALX4.
FC Image
HEK293T cells transfected with either RC224459 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-ALX4 antibody(TA505146), and then analyzed by flow cytometry.

 

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