Home Antibody All anti-ALOX5AP antibodies
Also for ALOX5AP (NM_001629)
|Peptide with sequence C-HKVEHESRTQNGR, from the internal region of the protein sequence according to NP_001620.2.|
|Test: Human. Expected from seq similarity: Human, Dog
||ELISA: 1:128,000. WB: 0.1-0.3µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
|Homo sapiens arachidonate 5-lipoxygenase-activating protein (ALOX5AP), transcript variant 1|
Entrez Gene 241 Human
Entrez Gene 477323 Dog
|This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. [provided by RefSeq]. |
|TransmembraneDruggable Genome |
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TA302488 (0.1µg/ml) staining of Human U937 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.