Home Antibody All anti-ALDOB antibodies
Anti-ALDOB TRUEMAB Antibody clone 5D1
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for ALDOB (NM_000035)
|Full length human recombinant protein of human ALDOB (NP_000026) produced in HEK293T cell.|
|| WB 1:2000, FLOW 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens aldolase B, fructose-bisphosphate (ALDOB)|
Entrez Gene 229 Human
|Fructose-1,6-bisphosphate aldolase (EC 126.96.36.199) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq, Dec 2008]. |
|Druggable Genome Glycolysis / GluconeogenesisPentose phosphate pathwayFructose and mannose metabolismMetabolic pathways|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ALDOB (RC220062, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ALDOB.
HEK293T cells transfected with either RC220062 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-ALDOB antibody(TA503062), and then analyzed by flow cytometry.