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Home Antibody All anti-ALDOB antibodies

Anti-ALDOB Antibody EPR3138Y

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA301312 Rabbit Monoclonal Antibody against ALDOB (Clone EPR3138Y) 100ul $325 In Stock
LC400007 ALDOB HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(5)
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Also for ALDOB (NM_000035)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Aldolase B was used as an immunogen.
Clone NameEPR3138Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500~1000; IHC: 1: 100~250; FC: 1:20
Predicted MW Explanation 39 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens aldolase B, fructose-bisphosphate (ALDOB)
Alternative NameALDB; ALDO2
Database LinkNP_000026
Entrez Gene 229 Human
Entrez Gene 230163 Mouse
Entrez Gene 24190 Rat
FunctionAldolase B is one of three known aldolase isoenzymes, and is found in kidney and small adult intestine where it is associated with aldolases A or C. Aldolase B catalyzes the reversible cleavage of fructose 1-phosphate into dihydroxyacetone phosphate and glyceraldehyde. It is involved in both glycolytic and gluconeogenic pathways, where its quaternary structure is critical for maintaining its full catalytic function. Hereditary fructose intolerance (HFI), a potentially fatal human autosomal recessive disease of carbohydrate metabolism, results with Aldolase B deficiency. Partially active Aldolase B, however, has been reported in an HFI individuals, which supports the hypothesis that adequate gluconeogenesis/glycolysis is maintained in HFI patients by the presence of partially active enzymes (1-4).
Related PathwayDruggable Genome Glycolysis / GluconeogenesisPentose phosphate pathwayFructose and mannose metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - ALDOB antibody [EPR3138Y]; Anti-ALDOB antibody [EPR3138Y] at 1/1000 dilution + fetal kidney lysate at 10 ug.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 39 kDa.Observed band size : 39 kDa.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ALDOB antibody [EPR3138Y]; TA301312, at 1/100 dilution, staining ALDOB in paraffin-embedded human liver tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-ALDOB antibody [EPR3138Y](TA301312); TA301312 showing positive staining in Normal kidney tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-ALDOB antibody [EPR3138Y](TA301312); TA301312 showing negative staining in Normal colon tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-ALDOB antibody [EPR3138Y](TA301312); TA301312 showing negative staining in Normal lung tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-ALDOB antibody [EPR3138Y](TA301312); TA301312 showing negative staining in Normal tonsil tissue.
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