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Anti-ALDH7A1 Antibody EP1934Y
Also for ALDH7A1 (NM_001182)
|A synthetic peptide corresponding to residues near the N-terminus of human Aldh7a1 was used as an immunogen.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:5,000; IHC: 1: 100; ICC: 1: 100; FC: 1:30; IP: 1:50
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Does not react with Rat
|Homo sapiens aldehyde dehydrogenase 7 family, member A1 (ALDH7A1), transcript variant 1|
|ATQ1; EPD; PDE|
|Antiquitin (Aldh7a1) is an evolutionarily conserved protein believed to play a role in the regulation of cellular turgor. Based on sequence analysis, this protein is classified as a member of the aldehyde dehydrogenase superfamily (1). Analysis of the amount of mRNA in various rat and human tissues indicates that the largest amounts are found in rat kidney and liver and in cultured human hepatoma cells. Only minimal amounts were detected in human peripheral blood leukocytes, rat lung, or cultured human fibroblasts (2). The plant homolog of ATQ1 is thought to be involved in regulating turgor pressure, a function that also would be essential for cells of the mammalian cochlea. Northern blots of 13 human fetal tissues show antiquitin to be highly expressed in cochlea, ovary, eye, heart, and kidney (3). |
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Western blot - ALDH7A1 antibody [EP1934Y]; All lanes : Anti-ALDH7A1 antibody [EP1934Y].Lane 1 : HepG2 cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : SW480 cell lysate.Lane 4 : SH-SY5Y cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP conjugated Goat anti-rabbit at 1/2000 dilution.Predicted band size : 55 kDa.Observed band size : 55 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ALDH7A1 antibody [EP1934Y]; Human liver tissue stained by ab68192 at 1/100 dilution.