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Home Antibody All anti-ALDH5A1 antibodies

Anti-ALDH5A1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306648
  • Rabbit Polyclonal Aldh5A1 Antibody
100ug 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenAldh5A1 antibody was raised against a 22 amino acid peptide near the carboxy terminus of the human Aldh5A1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens aldehyde dehydrogenase 5 family, member A1 (ALDH5A1), transcript variant 2
Alternative NameSSADH; SSDH
Database LinkNP_001071
Entrez Gene 7915 Human
Entrez Gene 214579 Mouse
Entrez Gene 291133 Rat
FunctionAldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist.
Related PathwayDruggable Genome Alanine, aspartate and glutamate metabolismButanoate metabolismMetabolic pathways

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Aldh5A1 in mouse liver lysate with Aldh5A1 antibody at (A) 1 and (B) 2 µg/ml.

 

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