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Home Antibody All anti-ALDH3A2 antibodies

Anti-ALDH3A2 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306639 Rabbit Polyclonal Aldh3A2 Antibody 100ug $325 3-7 Days
LC424995 ALDH3A2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for ALDH3A2 (NM_000382)
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OriGene Data

ImmunogenAldh3A2 antibody was raised against a 14 amino acid peptide near the carboxy terminus of the human Aldh3A2.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 1 - 2 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens aldehyde dehydrogenase 3 family, member A2 (ALDH3A2), transcript variant 2
Alternative NameALDH10; FALDH; SLS
Database LinkNP_000373
Entrez Gene 224 Human
Entrez Gene 11671 Mouse
FunctionAldh3A2 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjogren-Larrson syndrome, an inherited neurocutaneous disorder. Patients with this disorder display ichthyosis, mental retardation and spastic diplegia. The pathogenesis of the cutaneous and neurological symptoms is thought to result from abnormal lipid accumulation in the membranes of skin and brain, the formation of aldehyde Schiff base adducts with amine-containing lipids or proteins, or defective eicosanoid metabolism. At least four isoforms of Aldh3A2 are known to exist. This antibody is predicted to have no cross-reactivity to Aldh3A1.
Related PathwayTransmembraneDruggable Genome Glycolysis / GluconeogenesisAscorbate and aldarate metabolismFatty acid metabolismValine, leucine and isoleucine degradationLysine degradationArginine and proline metabolismMore Pathways >>

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WB Image
Western blot analysis of Aldh3A2 in mouse liver lysate with Aldh3A2 antibody at (A) 1 and (B) 2 µg/ml.


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