OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-ALDH3A2 antibodies

Anti-ALDH3A2 Antibody

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306639
  • Rabbit Polyclonal Aldh3A2 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424995) , 20ug Explanation
100ug 325 3-7 Days
Add to Shopping Cart
WB(1)
spacer
Also for ALDH3A2 (NM_000382)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenAldh3A2 antibody was raised against a 14 amino acid peptide near the carboxy terminus of the human Aldh3A2.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens aldehyde dehydrogenase 3 family, member A2 (ALDH3A2), transcript variant 2
Alternative NameALDH10; FALDH; SLS
Database LinkNP_000373
Entrez Gene 224 Human
Entrez Gene 11671 Mouse
FunctionAldh3A2 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjogren-Larrson syndrome, an inherited neurocutaneous disorder. Patients with this disorder display ichthyosis, mental retardation and spastic diplegia. The pathogenesis of the cutaneous and neurological symptoms is thought to result from abnormal lipid accumulation in the membranes of skin and brain, the formation of aldehyde Schiff base adducts with amine-containing lipids or proteins, or defective eicosanoid metabolism. At least four isoforms of Aldh3A2 are known to exist. This antibody is predicted to have no cross-reactivity to Aldh3A1.
Related PathwayTransmembraneDruggable Genome Glycolysis / GluconeogenesisAscorbate and aldarate metabolismFatty acid metabolismValine, leucine and isoleucine degradationLysine degradationArginine and proline metabolismMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Aldh3A2 in mouse liver lysate with Aldh3A2 antibody at (A) 1 and (B) 2 µg/ml.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title