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Home Antibody All anti-ALDH3A1 antibodies

Anti-ALDH3A1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306638
  • Rabbit Polyclonal Aldh3A1 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400232) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for ALDH3A1 (NM_000691)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenAldh3A1 antibody was raised against a 13 amino acid peptide near the carboxy terminus of the human Aldh3A1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens aldehyde dehydrogenase 3 family, member A1 (ALDH3A1), transcript variant 2
Alternative NameALDH3; ALDHIII
Database LinkNP_000682
FunctionAldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldh3A1 is highly expressed in stomach and even more strongly in cornea, representing between 5 to 50% of the water soluble protein fraction in mammalian corneas. It is thought that Aldh3A1 acts to protect the cornea from UV-induced oxidative stress by not only detoxification of reactive aldehydes by also through the direct absorbtion of UV energy. However, corneas from Aldh3A1-null mice are indistinguishable from those from wild-type mice; mice lacking both Aldh3A1 and Aldh1A1 showed increased cataract formation following UVB exposure, suggesting that Aldh1A1 may be able to compensate for the loss of Aldh3A1. At least two isoforms of Aldh3A1 are known to exist. This antibody is predicted to have no cross-reactivity to Aldh3A2.
Related Pathway

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WB Image
Western blot analysis of Aldh3A1 in human stomach lysate with Aldh3A1 antibody at (A) 1 and (B) 2 µg/ml.

 

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