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Anti-AKT1 Antibody M1843


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA307635 Rabbit monoclonal antibody against Akt1(clone M1843) 100ul $379 In Stock
LC423056 AKT1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for AKT1 (NM_001014431)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Akt1 was used as an immunogen.
Clone NameM1843 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens v-akt murine thymoma viral oncogene homolog 1 (AKT1), transcript variant 3
Database LinkNP_001014431
Entrez Gene 207 Human
FunctionAkt1/PKBa is a serine/threonine protein kinase whose kinase activity plays a key role in cellular functions such as apoptosis, glycogen synthesis, and cell growth. Moreover, it plays a role in glucose transport by mediating insulin-induced translocation of the GLUT4 glucose transporter to the cell surface (2). It promotes glycogen synthesis by mediating the insulin-induced activation of glycogen synthase. Akt1/PKBa is activated by various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), and insulin and insulin-like growth factor I (IGF-I) (1, 2). Defects in Akt1 are associated with breast, colorectal, and ovarian cancer (2).
Related PathwayProtein KinaseES Cell Differentiation/IPSDruggable Genome MAPK signaling pathwayErbB signaling pathwayChemokine signaling pathwaymTOR signaling pathwayApoptosisVEGF signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - antibody [M1843]; All lanes : Anti-AKT1 antibody [M1843] at 1/1000 dilution.Lane 1 : MCF7 cell lysate .Lane 2 : HeLa cell lysate .Lane 3 : A431 cell lysates.Lane 4 : A549 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 56 kDa.


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