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Anti-AKT1 Antibody M1843
Also for AKT1 (NM_001014431)
|A synthetic peptide corresponding to residues in human Akt1 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC,IHC-P or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens v-akt murine thymoma viral oncogene homolog 1 (AKT1), transcript variant 3|
|AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA|
|Akt1/PKBa is a serine/threonine protein kinase whose kinase activity plays a key role in cellular functions such as apoptosis, glycogen synthesis, and cell growth. Moreover, it plays a role in glucose transport by mediating insulin-induced translocation of the GLUT4 glucose transporter to the cell surface (2). It promotes glycogen synthesis by mediating the insulin-induced activation of glycogen synthase. Akt1/PKBa is activated by various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), and insulin and insulin-like growth factor I (IGF-I) (1, 2). Defects in Akt1 are associated with breast, colorectal, and ovarian cancer (2).|
Delta-Notch Signaling Pathway
EGFR1 Signaling Pathway
Jak-STAT signaling pathway
MAPK signaling pathway
Signaling by GPCR
Toll-like receptor signaling pathway
Wnt Signaling Pathway
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Western blot - antibody [M1843]; All lanes : Anti-AKT1 antibody [M1843] at 1/1000 dilution.Lane 1 : MCF7 cell lysate .Lane 2 : HeLa cell lysate .Lane 3 : A431 cell lysates.Lane 4 : A549 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 56 kDa.