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Anti-AKT1 Antibody M1843
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for AKT1 (NM_001014431)
|A synthetic peptide corresponding to residues in human Akt1 was used as an immunogen.|
|Store at -20C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.|
|Homo sapiens v-akt murine thymoma viral oncogene homolog 1 (AKT1), transcript variant 3|
|AKT; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA|
|Akt1/PKBa is a serine/threonine protein kinase whose kinase activity plays a key role in cellular functions such as apoptosis, glycogen synthesis, and cell growth. Moreover, it plays a role in glucose transport by mediating insulin-induced translocation of the GLUT4 glucose transporter to the cell surface (2). It promotes glycogen synthesis by mediating the insulin-induced activation of glycogen synthase. Akt1/PKBa is activated by various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), and insulin and insulin-like growth factor I (IGF-I) (1, 2). Defects in Akt1 are associated with breast, colorectal, and ovarian cancer (2).|
Delta-Notch Signaling Pathway
EGFR1 Signaling Pathway
Jak-STAT signaling pathway
MAPK signaling pathway
Signaling by GPCR
Toll-like receptor signaling pathway
Wnt Signaling Pathway
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Western blot analysis on (A) MCF-7, (B) HeLa, (C) A431, and (D) A549 cell lysates using anti-Akt1 RabMAb .