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Home Antibody All anti-AKT1 antibodies

Anti-AKT1 Antibody M1843

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307635
  • Rabbit monoclonal antibody against Akt1(clone M1843)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC423056) , 20ug Explanation
100ul 379 In Stock
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Also for AKT1 (NM_001014431)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Akt1 was used as an immunogen.
Clone NameM1843 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens v-akt murine thymoma viral oncogene homolog 1 (AKT1), transcript variant 3
Alternative NameAKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA
Database LinkNP_001014431
Entrez Gene 207 Human
FunctionAkt1/PKBa is a serine/threonine protein kinase whose kinase activity plays a key role in cellular functions such as apoptosis, glycogen synthesis, and cell growth. Moreover, it plays a role in glucose transport by mediating insulin-induced translocation of the GLUT4 glucose transporter to the cell surface (2). It promotes glycogen synthesis by mediating the insulin-induced activation of glycogen synthase. Akt1/PKBa is activated by various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), and insulin and insulin-like growth factor I (IGF-I) (1, 2). Defects in Akt1 are associated with breast, colorectal, and ovarian cancer (2).
Related PathwayProtein KinaseES Cell Differentiation/IPSDruggable Genome MAPK signaling pathwayErbB signaling pathwayChemokine signaling pathwaymTOR signaling pathwayApoptosisVEGF signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - antibody [M1843]; All lanes : Anti-AKT1 antibody [M1843] at 1/1000 dilution.Lane 1 : MCF7 cell lysate .Lane 2 : HeLa cell lysate .Lane 3 : A431 cell lysates.Lane 4 : A549 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 56 kDa.

 

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