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Home Antibody All anti-AGT antibodies

Anti-AGT Antibody EPR2931

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307762
  • Rabbit monoclonal antibody against Angiotensinogen(clone EPR2931)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400005) , 20ug
100ul $325 3-7 Days
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WB(1)
IF(1)
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Also for AGT (NM_000029)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Angiotensinogen was used as an immunogen.
Clone NameEPR2931 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; ICC/IF: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IHC-P.

Reference Data

Target NameHomo sapiens angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (AGT)
Alternative NameANHU; SERPINA8
Database LinkNP_000020
FunctionAngiotensinogen is a precursor of angiotensin-1 and a member of the serpin family, expressed by the liver and secreted in plasma. Angiotensinogen contains angiotensin-1, 2, and 3. In response to lowered blood pressure, remin cleaves angiotensinogen and produce angiotensin-1 (1). Angiotensin-converting enzyme (ACE) further removes a dipeptide to produce the physiologically active peptide angiotensin-2. Angiotensin-2 is involved in regulating mineral balance and volume of body fluids, while angiotensin-3 stimulates aldosterone release (2). In humans, angiotensinogen is 118 amino acids long, but its size varies between species. Defects in angiotensinogen have been linked to renal tubular dygenesis (RTD) and susceptibility to essential hypertension (3).
Related Pathway
Adipogenesis
Signaling by GPCR

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WB Image
Western blot - Angiotensinogen antibody [EPR2931]; All lanes : Anti-Angiotensinogen antibody [EPR2931] at 1/1000 dilution.Lane 1 : Human fetal artery lysate.Lane 2 : Human fetal heart lysate.Lane 3 : Human fetal liver lysate.Lane 4 : HepG2 lysate.Lane 5 : 293T lysate.Lane 6 : Human plasma lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 53 kDa.
IF Image
Immunocytochemistry/ Immunofluorescence - Angiotensinogen antibody [EPR2931]; TA307762, at 1/100 dilution, staining Angiotensinogen in HepG2 cells by Immunofluorescence.

 

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