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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-ADSL antibodies

Anti-ADSL TrueMAB Antibody clone 2D10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA501810
  • Purified ADSL (Adenylosuccinate Lyase) mouse monoclonal antibody, clone 2D10
  • FREE positive control: HEK293T cell transient overexpression lysate (LC424970) , 20ug
 100ul $379 In Stock Add to Shopping Cart
CF501810
  • Carrier-free (BSA/glycerol-free) ADSL mouse monoclonal antibody, clone 2D10
100ug $450 3-4 weeks Add to Shopping Cart
WB(2)
IHC(9)
FC(1)
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Also for ADSL (NM_000026)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens adenylosuccinate lyase (ADSL), transcript variant 1
Synonyms:AMPS; ASASE; ASL
ImmunogenFull length human recombinant protein of human ADSL (NP_000017) produced in HEK293T cell.
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone Nameclone 2D10 IsotypeIgG1
Species ReactivityHuman, Dog, Rat, Monkey Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB 1:500~2000, IHC 1:150, FLOW 1:100
BackgroundAdenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ADSL (RC200524, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ADSL.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-ADSL monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-ADSL mouse monoclonal antibody. (TA501810)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-ADSL mouse monoclonal antibody. (TA501810)
IHC Image
Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-ADSL mouse monoclonal antibody. (TA501810)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-ADSL mouse monoclonal antibody. (TA501810)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-ADSL mouse monoclonal antibody. (TA501810)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-ADSL mouse monoclonal antibody. (TA501810)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-ADSL mouse monoclonal antibody. (TA501810)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-ADSL mouse monoclonal antibody. (TA501810)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-ADSL mouse monoclonal antibody. (TA501810)
FC Image
HEK293T cells transfected with either RC200524 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-ADSL antibody(TA501810), and then analyzed by flow cytometry.

 

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