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Anti-ADIPOR1 Antibody EPR6626
Also for ADIPOR1 (NM_001127687)
|A synthetic peptide corresponding to residues in the intracellular domain of human Adiponectin receptor 1 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, IHC, FC
||WB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100; FC: 1:100 - 1:500; ICC/IF: 1:100 - 1:250
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for IP.
|Homo sapiens adiponectin receptor 1 (ADIPOR1), transcript variant 2|
|ACDCR1; CGI-45; CGI45; FLJ25385; FLJ42464; PAQR1; TESBP1A|
Entrez Gene 51094 Human
Entrez Gene 72674 Mouse
Entrez Gene 289036 Rat
|Adiponectin receptor 1 is a receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. It is involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Adiponectin receptor 1 mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. This protein has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin (1). |
|TransmembraneDruggable Genome Adipocytokine signaling pathway|
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Western blot - Anti-Adiponectin Receptor 1 antibody [EPR6626]; All lanes : Anti-Adiponectin Receptor 1 antibody [EPR6626] at 1/1000 dilution.Lane 1 : Human muscle lysate.Lane 2 : Human heart lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat Anti-rabbit HRP at 1/2000 dilution.Predicted band size : 43 kDa.
Other-Anti-Adiponectin Receptor 1 antibody [EPR6626](TA310173); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Adiponectin Receptor 1 antibody [EPR6626]; TA310173, at 1/50 dilution, staining Adiponectin Receptor 1 in Formalin-fixed, Paraffin-embedded Human kidney tissue by Immunohistochemistry
Flow Cytometry-Anti-Adiponectin Receptor 1 antibody [EPR6626](TA310173); Overlay histogram showing HepG2 cells stained with TA310173 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody for 30 min at 22°C. The secondary antibody used was DyLight 488 goat anti-rabbit IgG (H+L) at 1/500 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) ( 1ug/1x10^6 cells) used under the same conditions. Acquisition of >5,000 events was performed.