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Home Antibody All anti-ADIPOR1 antibodies

Anti-ADIPOR1 Antibody EPR6626

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310173
  • Rabbit Monoclonal antibody against Adiponectin receptor 1 (ADIPOR1)
100ul 325 In Stock
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WB(1)
IHC(1)
FC(1)
Assay(1)
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Also for ADIPOR1 (NM_001127687)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the intracellular domain of human Adiponectin receptor 1 was used as an immunogen.
Clone NameEPR6626 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC, FC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100; FC: 1:100 - 1:500; ICC/IF: 1:100 - 1:250
Predicted MW Explanation 43 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens adiponectin receptor 1 (ADIPOR1), transcript variant 2
Alternative NameACDCR1; CGI-45; CGI45; FLJ25385; FLJ42464; PAQR1; TESBP1A
Database LinkNP_001121159
Entrez Gene 51094 Human
Entrez Gene 72674 Mouse
Entrez Gene 289036 Rat
FunctionAdiponectin receptor 1 is a receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. It is involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Adiponectin receptor 1 mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. This protein has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin (1).
Related PathwayTransmembraneDruggable Genome Adipocytokine signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Adiponectin Receptor 1 antibody [EPR6626]; All lanes : Anti-Adiponectin Receptor 1 antibody [EPR6626] at 1/1000 dilution.Lane 1 : Human muscle lysate.Lane 2 : Human heart lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat Anti-rabbit HRP at 1/2000 dilution.Predicted band size : 43 kDa.
Assay Image
Other-Anti-Adiponectin Receptor 1 antibody [EPR6626](TA310173); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Adiponectin Receptor 1 antibody [EPR6626]; TA310173, at 1/50 dilution, staining Adiponectin Receptor 1 in Formalin-fixed, Paraffin-embedded Human kidney tissue by Immunohistochemistry
FC Image
Flow Cytometry-Anti-Adiponectin Receptor 1 antibody [EPR6626](TA310173); Overlay histogram showing HepG2 cells stained with TA310173 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody for 30 min at 22°C. The secondary antibody used was DyLight 488 goat anti-rabbit IgG (H+L) at 1/500 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) ( 1ug/1x10^6 cells) used under the same conditions. Acquisition of >5,000 events was performed.

 

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