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Home Antibody All anti-ADAM17 antibodies

Anti-ADAM17 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302775
  • Goat Polyclonal Antibody against ADAM17
100ug 325 3-7 Days
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WB(2)

OriGene Data

Immunogen Peptide with sequence LQRQNRVDSKETEC, from the C Terminus of the protein sequence according to NP_003174.3.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:128,000. WB: 0.1-0.3µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens ADAM metallopeptidase domain 17 (ADAM17)
Alternative NameADAM18; CD156B; CSVP; NISBD; TACE
Database LinkNP_003174
Entrez Gene 6868 Human
Entrez Gene 11491 Mouse
Entrez Gene 57027 Rat
FunctionThis gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq].
Related PathwayTransmembraneProteaseDruggable Genome Notch signaling pathwayAlzheimer's diseaseEpithelial cell signaling in Helicobacter pylori infection

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA302775 staining (0.2µg/ml) of Hela lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
WB Image
TA302775 staining (0.3µg/ml) of Daudi (A), Jurkat (B) and HeLa (C) lysates (35µg total protein in RIPA buffer). Primary incubated for 1 hour. Detected by chemiluminescence.

 

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