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Anti-ACY1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308034 Rabbit polyclonal antibody to Aminoacylase-1 (aminoacylase 1) 100ul $325 3-7 Days
LC424578 ACY1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 89 and 366 of Aminoacylase 1 (Uniprot ID#Q03154)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Pig, Rat, Bovine) Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 46kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (85%), Pig (86%), Rat (86%), Bovine (87%)

Reference Data

Target NameHomo sapiens aminoacylase 1 (ACY1), transcript variant 1
Alternative NameACY-1; ACY1D; HEL-S-5
Database LinkNP_000657
Entrez Gene 95 Human
Entrez Gene 109652 Mouse
Entrez Gene 300981 Rat
Function Aminoacylase-1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. ACY1 has been assigned to chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and ACY1 is the first member of a new family of zinc-binding enzymes. [provided by RefSeq]
Related PathwayProtease Arginine and proline metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: H1299. 10% SDS PAGE. TA308034 diluted at 1:1000.
Aminoacylase 1 antibody [N2C3-2] detects Aminoacylase-1 protein at cytoplasm on placenta by immunohistochemical analysis. Sample: Paraffin-embedded placenta. Aminoacylase 1 antibody [N2C3-2] (TA308034) dilution: 1:100.
Immunofluorescence analysis of paraformaldehyde-fixed A431, using Aminoacylase-1(TA308034) antibody at 1:200 dilution.


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