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Anti-ACTN3 Antibody EP2531Y


Specifications Citations (2) Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA303381 Rabbit monoclonal antibody against Alpha-Actinin 3 (EP2531Y ) 100ul $325 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the N-terminus of human alpha-actinin 3 was used as an immunogen.
Clone NameEP2531Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:5000 - 10,000; IHC: 1:100 - 250; ICC: 1:100 - 250; FC: 1:100 - 250
Predicted MW Explanation 103 kDa
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens actinin alpha 3 (gene/pseudogene) (ACTN3), transcript variant 1, coding
Alternative NameMGC117002; MGC117005
Database LinkNP_001095
Entrez Gene 89 Human
Entrez Gene 11474 Mouse
Entrez Gene 171009 Rat
FunctionAlpha-actinin is an actin-binding protein with multiple roles in different cell types. This gene expression is limited to skeletal muscle. It is localized to the Z-disc and analogous dense bodies, where it helps to anchor the myofibrillar actin filaments [provided by RefSeq].
Related Pathway Focal adhesionAdherens junctionTight junctionLeukocyte transendothelial migrationRegulation of actin cytoskeletonSystemic lupus erythematosusMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - ACTN3 antibody [EP2531Y]; Anti-ACTN3 antibody [EP2531Y] at 1/10000 dilution + human skeletal muscle lysate at 10 ug.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 103 kDa.Observed band size : 103 kDa.

IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ACTN3 antibody [EP2531Y]; Immunohistochemical analysis of paraffin-embedded human muscle tissue using TA303381 at 1/100-1/250 dilution.


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